Axentri 150mg Tablets are an antiretroviral drug belonging to the chemokine receptor antagonist category, containing the active ingredient Maraviroc. It is used to treat only CCR5-tropic human immunodeficiency virus type 1 (HIV-1) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken in combination with other medicines used to treat HIV infection.
This drug is contraindicated in individuals with severe renal impairment and may have altered drug clearance, which mainly affects the efficacy and safety of the medicine. Also, it is highly advised not to use this drug in patients with severe renal impairment. Dose adjustment is necessary for such conditions. The liver metabolizes this medicine, specifically through the cytochrome P450 enzyme. In patients with liver impairment, the clearance of Axentri 150mg Tablet may be reduced, leading to increased drug concentrations in the bloodstream. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual.
It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be immediately discontinued the drug and appropriate medical treatment initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this Axentri 150mg Tablets.
Uses of Axentri 150mg TabletHuman Immunodeficiency Virus (HIV) Therapeutic Effects of Axentri 150mg Tablet
Axentri 150mg Tablet blocks a receptor named CCR5, which HIV uses to enter and infect your blood cells. This drug mainly prevents HIV from binding to and entering the CD4+ T cells, inhibiting the virus's ability to replicate and spread. Interaction of Axentri 150mg Tablet with other drugsInform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications, such as efavirenz, may interact with Axentri 150mg Tablet and reduce effectiveness by causing undesirable side effects. More Information about Axentri 150mg Tablet Store Axentri 150mg Tablet at room temperature (15°to 25°C).Keep the tablet out of reach of children and pets.How to consume Axentri 150mg TabletIt is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take a Axentri 150mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water.Safety Advices for Axentri 150mg Tablet
Pregnancy
Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Axentri 150mg Tablet.
Breast Feeding
Only limited studies are available regarding the safety of Axentri 150mg Tablet use during breastfeeding. Consult with your doctor for more advice.
Lungs
It is unknown whether Axentri 150mg Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Consult your physician for advice before taking Axentri 150mg Tablet if you have liver problems. Ensure that your physician monitors your liver functions regularly.
Alcohol
Consuming alcohol may affect the effectiveness of Axentri 150mg Tablet. It is highly advised to stop consuming alcohol if you take this medicine.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking the Axentri 150mg Tablet, it may cause dizziness and impair concentration.
Side Effects of Axentri 150mg TabletSide Effects:Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Swelling of the face, lips, or tongue
- Difficulty breathing
- Widespread skin rash
- Fever (high temperature)
- Blisters and peeling skin, particularly around the mouth, nose, eyes, and genitals.
Common
- Diarrhea
- Stomach ache
- Loss of appetite
- Headache
- Sleeping problems
- Depression
- Feeling weak or lack of energy
- Anaemia
- Increase in liver enzymes
Word of AdviceTo prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything that can have blood or body fluids on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus.FAQs Q 1. How does Axentri 150mg Tablet work in HIV?Axentri 150mg Tablet works by blocking a receptor called CCR5, which HIV uses to enter and infect your blood cells. This drug mainly prevents HIV from binding to and entering the CD4+ T cells, inhibiting the virus's ability to replicate and spread.
Q 2. Do I need to take a Axentri 150mg Tablet with food?No. Axentri 150mg Tablets can be taken with or without food.
Q 3. What medicines should I avoid with the Axentri 150mg Tablet?It is important to make your healthcare provider aware of any medicines you take, including herbal, complementary, or other medicines you may buy from the pharmacy or online, to ensure that they are compatible with Axentri 150mg Tablet and any other anti-HIV drugs you are taking.
Q 4. Do I get hepatic impairment when taking this Axentri 150mg Tablet?The liver metabolizes this drug, so individuals with severe hepatic impairment should avoid taking Axentri 150mg Tablets. It is necessary to consult with your doctor to determine the appropriateness of this medicine in individuals with liver problems.
Q 5. How to take Axentri 150mg Tablet?Always take this Axentri 150mg Tablet exactly as your doctor has prescribed you. If you are unsure how to take it, just check it with your doctor. Your doctor will advise you whether taking this drug as an oral solution is better if you (or your child) cannot swallow tablets.
Q 6. Who should not take Axentri 150mg Tablet?People with a previous allergic reaction or hypersensitivity to Axentri 150mg Tablet or any of its components should not take this medication.
Q 7. Why should Axentri 150mg Tablets not be taken by individuals with peanut or soya allergies?Maraviroc contains soya lecithin, so you should not take the Axentri 150mg Tablet if you have a peanut or soya allergy.
Q 8. What if I miss my Axentri 150mg Tablet?If you miss a dose of this drug or if it is almost time for the next dose, do not take the missed dose. Wait and take the next dose of Axentri 150mg Tablet at its regular time.
Fact Box of Axentri 150mg TabletMolecule name: Maraviroc | Therapeutic class: Antiretroviral |
Pharmacological class: Chemokine receptor antagonist | Indications: Human Immunodeficiency Virus (HIV) |
